Investigator / Supervisor details

Name	Professor Steve Homans
Current Institution	University of Leeds
Current Department	Sch of Molecular & Cellular Biology
Institution website	http://www.leeds.ac.uk
Previous Institutions	University of St Andrews

Current Awards

No current BBSRC awards

Completed Awards

Reference	Title	Award Role	Value £	Type
00/B1/B/06200	Chemical and biophysical tools for studying ligand-protein interactions	Principal Supervisor	37,126	Studentships
95/A3/B/00503	Antibody-antigen binding studied by NMR spectroscopy of a peptide antigen in complex with an antibody Fv fragment	Principal Supervisor	30,553	Studentships
97/A1/B/03503	NMR structure determination of the metalloregulatory protein, MerR	Principal Supervisor	32,558	Studentships
B06636	Studies on oligosaccharide-protein interactions using novel heteronuclear NMR techniques at low temperature	Principal Investigator	151,846	Research Grant
B12992	A new approach to the derivation of per-residue thermodynamic parameters for ligand-protein interactions	Principal Investigator	219,980	Research Grant
B12993	Probing membrane transport protein-ligand complexes by use of residual dipolar and quadrupolar couplings	Principal Investigator	235,276	Research Grant
B14097	Three-dimensional structure of the vacuolar H+-ATPase	Co-investigator	1,021,012	Research Grant
B16723	NMR investigations of the solution structure and dynamics of the MS2 bacteriophage translational operator coat protein and their complexes	Co-investigator	207,456	Research Grant
B17173	Elucidation of the three-dimensional structure of the exocyst complex	Co-investigator	662,372	Research Grant
B19388	Dynamics and thermodynamics of recognition of ligands by the major urinary protein	Principal Investigator	209,544	Research Grant
BB/C500679/1	Role of solvation in the affinity and specificity of ligand-protein interactions	Principal Investigator	97,277	Research Grant
BB/D01025X/1	Role of dynamics in the initiation of RNA bacteriophage assembly	Principal Investigator	65,692	Research Grant
BB/E000991/1	Thermodynamics of 'hydrophobic' versus 'hydrophilic' binding in ligand-protein complexes	Principal Investigator	322,841	Research Grant
BB/E013163/1	A high-throughput protein expression facility for structural and cell biology	Co-investigator	233,230	Research Grant
BB/E014844/1	Using NMR-derived restraints in combination with molecular dynamics simulations to derive thermodynamic parameters for biomolecular interactions.	Principal Investigator	178,548	Research Grant
BB/H018433/1	Molecular dissection of a novel protein-protein interaction: structure and mechanism of the staphylococcal fusidic acid-resistance protein FusB	Co-investigator	306,782	Research Grant
BBS/B/05680	Conformational dynamics and catalysis of aldolase studied by NMR spectroscopy	Co-investigator	207,944	Research Grant
JEI09435	Structural and thermodynamic studies of biomolecular interactions	Principal Investigator	25,144	Research Grant
MOL04547	Design and synthesis of inhibitors of carbohydrate-protein interactions	Principal Investigator	123,914	Research Grant
REI18440	Molecular and cellular biology of membranes	Co-investigator	185,488	Research Grant
REI20490	Enhanced computing infrastructure for structural biology and bioinformatics at the University of Leeds	Co-investigator	197,958	Research Grant
SBD07527	Structure-based inhibitor design and vaccine development using carbohydrate-binding bacterial toxins	Principal Investigator	236,406	Research Grant

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