Award details

Structural and thermodynamic studies of biomolecular interactions

Reference	JEI09435
Principal Investigator / Supervisor	Professor Steve Homans
Co-Investigators / Co-Supervisors
Institution	University of St Andrews
Department	Biology
Funding type	Research
Value (£)	25,144
Status	Completed
Type	Research Grant
Start date	05/02/1998
End date	05/08/1998
Duration	6 months

Abstract

This equipment grant application is a request for funds to set up a multifunctional blot and gel imaging system that will provide phosphorimaging, fluorescence and quantitative densitometry facilities in a single package. Three separate projects are described in detail which will make use of these facilities. Each of these will greatly benefit from the increased speed and sensitivity, large dynamic range and accurate quantitative nature of the imaging capabilities of the system. These are: 1) Identification of the physiological eIF4E kinase from Xenopus laevis eggs and serum- stimulated cells; Quantification of the level of phosphorylation of eIF4E in response to cell growth; Mapping of the mitogen-stimulated phosphorylation sites on eIF4G. 2) Cell cycle control in B lymphocytes. 3) Studies on membrane protein assembly.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Research Equipment Initiative 1997 (JE2) [1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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