BBSRC Portfolio Analyser
Investigator / Supervisor details
Name
Professor Anthony Maxwell
Current Institution
John Innes Centre
Current Department
Biological Chemistry
Institution website
http://www.jic.ac.uk
Previous Institutions
University of Leicester
Current Awards
Reference
Title
Award Role
Value £
Type
BB/V006983/1
Exploring novel binding pockets in DNA gyrase and DNA topoisomerase IV to address antibiotic resistance
Principal Investigator
504,268
Research Grant
BBS/E/J/000CA436
More Medicines for Tuberculosis
Principal Investigator
203,422
Institute Project
BBS/E/J/000CA547
European Gram Negative Antibacterial Engine
Principal Investigator
137,264
Institute Project
BBS/E/J/000PR9791
Biological Context
Co-investigator
6,824,489
Institute Project
Completed Awards
Reference
Title
Award Role
Value £
Type
9810615
The interaction of DNA gyrase with FdhE a protein involved in the assembly of the formate dehydrogenase complex
Principal Investigator
138,336
Research Grant
B05792
The mechanism of action of DNA gyrase and other topoisomerases
Principal Investigator
142,581
Research Grant
B19400
The aminocoumarin biosynthetic gene clusters of Streptomyces: structural and functional analysis
Co-investigator
214,676
Research Grant
BB/C517376/1
Energy coupling in type II topoisomerases: why do they hydrolyse ATP?
Principal Investigator
218,193
Research Grant
BB/E013074/1
Measuring biomolecular interactions using the Biacore T100
Principal Investigator
201,197
Research Grant
BB/I002049/1
The molecular basis of the action of the antibiotic simocyclinone D8 on DNA gyrase
Principal Investigator
457,811
Research Grant
BB/I019294/1
Understanding supercoiling-dependent DNA recognition: a combined experimental and computational approach
Principal Investigator
437,374
Research Grant
BB/J011843/1
Exploiting the insect gut to discover novel plant-derived antibiotics and explore naturally-occurring antibiotic resistance
Principal Investigator
92,173
Training Grants
BB/J016853/1
The molecular basis of action of the toxin Microcin B17 on DNA gyrase
Principal Investigator
480,971
Research Grant
BB/J020222/1
Building Links between JIC and CAS: Towards a CAS-JIC Joint Centre
Co-investigator
30,244
Research Grant
BB/P021506/1
Identifying the biosynthetic origins of nybomycin, a reverse antibiotic
Co-investigator
516,560
Research Grant
BB/R001243/1
Tackling tricky twists - how does DNA gyrase function inside living cells?
Principal Investigator
79,060
Research Grant
BBS/E/J/00000201
Structure and function of DNA topoisomerases and associated proteins: their role in biological processes, and their exploitation in chemotherapeutics
Principal Investigator
2,227,611
Institute Project
BBS/E/J/00004019
The interaction of DNA gyrase with FdhE, a protein involved in the assembly of the formate dehydrogenase complex
Principal Investigator
44,597
Institute Project
BBS/E/J/00004020
The mechanism of DNA cleavage by DNA gyrase
Principal Investigator
15,379
Institute Project
BBS/E/J/0000A004
Characterisation of the mode of action of the bacterial toxin microcin B17, a novel inhibitor of DNA gyrase
Principal Investigator
41,764
Institute Project
BBS/E/J/0000A079
DNA gyrase from Arabidopsis thaliana
Principal Investigator
43,607
Institute Project
BBS/E/J/0000A135
DNA topoisomerase VI, an archaeal enzyme with a role in cell-size control, cell cycle and endoreduplication in Arabidopsis
Principal Investigator
80,541
Institute Project
BBS/E/J/0000A153
The aminocoumarin biosynthetic gene clusters of streptomyces: structural and functional analysis
Co-investigator
176,548
Institute Project
BBS/E/J/0000A181
Development of New Gyrase Inhibitors by Combinatorial Biosynthesis (CombiGyrase)
Principal Investigator
181,567
Institute Project
BBS/E/J/0000A224
Energy coupling in type II topoisomerases: why do they hydrolyse ATP?
Principal Investigator
172,630
Institute Project
BBS/E/J/0000X019
X-ray crystallography of DNA gyrase
Principal Investigator
10,351
Institute Project
BBS/E/J/000CA349
The molecular basis of post-initiation regulation of RNA transcription
Principal Investigator
119,643
Institute Project
BBS/E/J/000CA437
The molecular basis of the action of the antibiotic simocyclinone D8 on DNA gyrase
Principal Investigator
131,206
Institute Project
BBS/E/J/000CA455
Understanding supercoiling-dependent DNA recognition: a combined experimental and computational approach
Principal Investigator
149,315
Institute Project
BBS/E/J/000CA498
The molecular basis of action of the toxin Microcin B17 on DNA gyrase
Principal Investigator
165,541
Institute Project
BBS/E/J/000CA676
Identifying the Biosynthetic Origins of Nybomycin, a Reverse Antibiotic
Co-investigator
8,469
Institute Project
BBS/S/D/2005/13248
Structural studies of toposiomerase complexes (Funded via Training Grant BB/B511927/1)
Principal Supervisor
Studentships
C15130
Characterisation of the mode of action of the bacterial toxin Microcin B17 a novel inhibitor of DNA gyrase
Principal Investigator
169,200
Research Grant
C17465
DNA gyrase from Arabidopsis thaliana
Principal Investigator
212,396
Research Grant
G18653
DNA topoisomerase VI anarchael enzyme with a role in cell-size controlcell cycle and endoreduplication in Arabidopsis
Principal Investigator
222,384
Research Grant
JEI09276
Conformational analysis of biomolecules by CD spectroscopy: structural and dynamic studies
Co-investigator
42,504
Research Grant
SBD07572
Drug discovery and DNA gyrase
Principal Investigator
139,673
Research Grant
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