BBSRC Portfolio Analyser

Investigator / Supervisor details

NameProfessor Jon Waltho
Current InstitutionThe University of Manchester
Current DepartmentChemistry
Institution websitehttp://www.man.ac.uk
Previous InstitutionsUniversity of Sheffield

Current Awards

ReferenceTitleAward RoleValue £Type
BB/S007695/1 The Control of Non-Chemical Steps in Enzyme Catalysis Principal Investigator 475,003 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
00/A2/B/06430 The folding pathway of PGK Principal Supervisor 37,126 Studentships
01/A2/B/07435 Photoactivation of protein folding Principal Supervisor 39,359 Studentships
01/B1/B/07441 Recruitment of PrPc by it's alternative monomeric beta form Principal Supervisor 39,359 Studentships
94/B1/B/00959 Effect of phosphorylation on protein and disulphide bond stability using NMR spectroscopy Principal Supervisor 29,397 Studentships
95/A2/B/00427 Structural characterisation of the chemokine LD78 Principal Supervisor 30,553 Studentships
99/B1/C/05433 Molecular basis of apoptosis inhibition by IAPs Principal Supervisor 35,135 Studentships
B11984 Protein folding intermediates versus unfolded state ensembles Principal Investigator 239,924 Research Grant
B14739 An NMR investigation of the mechanism of action of uridine DNA glycosylase; a remarkably effective DNA repair system Co-investigator 126,588 Research Grant
B17948 How unfolded is the unfolded state of proteins and can it direct folding pathways? Principal Investigator 197,604 Research Grant
BB/C504035/1 The moleculecular structure of cystatin amyloid fibrils Co-investigator 195,056 Research Grant
BB/D01798X/1 Residue-specific contributions to the energetics of the catalytic cycle of PGK Principal Investigator 418,950 Research Grant
BB/E017541/1 The influence of metal fluorides on the structure and dynamics of phosphoryl transfer enzymes Principal Investigator 400,271 Research Grant
BB/H000844/1 Atomic resolution experimental interrogation of hydride quantum tunnelling in enzyme reaction chemistry Principal Investigator 414,672 Research Grant
BB/H017208/1 Towards a systems-level understanding of the novel redox-regulated mitochondrial protein import and disulphide bond formation pathway Co-investigator 347,186 Research Grant
BB/I002146/1 Understanding enzyme-catalysed phosphoryl transfer Principal Investigator 464,275 Research Grant
BB/K009079/1 Conformation, Reactivity, Dynamics and Selectivity of FEN Family Proteins Relevant to Replication and Repair. Co-investigator 474,762 Research Grant
BB/K016245/1 Dynamics, Gating and Opening in Enzyme Catalysis Principal Investigator 383,035 Research Grant
BB/M011658/1 An advanced multi-purpose instrument for biological ultrafast time resolved spectroscopy Co-investigator 491,200 Research Grant
BB/M021637/1 Enzyme catalysis of nucleophilic attack of anions by anions Principal Investigator 341,608 Research Grant
BB/P002927/1 A molecular mechanism for a general amyloid re-modelling activity Co-investigator 527,681 Research Grant
BB/P010180/1 Interrogation of the catalytic properties of MhuD - a crucial heme oxygenase in Mycobacterium tuberculosis Co-investigator 448,944 Research Grant
BB/R000727/1 Upgrade to 600 MHz NMR spectrometer Co-investigator 450,352 Research Grant
BB/R018251/1 Conformational Dynamics of Two-Way DNA Junctions Co-investigator 475,898 Research Grant
BB/S003320/1 Catechol-O-methyltransferase (COMT): Resolving the mechanism of an archetypical methyl transferase with new experimental tools Co-investigator 509,991 Research Grant
BB/V019341/1 BEACON - A multi-user and multi-project facility for biological macromolecules and nanoparticles characterization in solution Co-investigator 411,229 Research Grant
BBS/B/10218 Ultrafast folding of PGK using laser photolysis Principal Investigator 291,667 Research Grant
BBS/S/C/2002/12855 Structural investigations of vesicular trafficking proteins (Funded via Training Grant BB/A517750/1) Principal Supervisor Studentships
BBS/S/D/2004/12621 Ultrafast reactions in protein folding (Funded via Training Grant BB/A517750/1) Principal Supervisor Studentships
C18024 Structure and binding specificity of the vesicular trafficking protein SNX1 Principal Investigator 191,928 Research Grant
E15611 Templated in situ assembly for the delivery of multi-site ligands Co-investigator 166,144 Research Grant
EGH16083 The road to drug discovery: structure-function studies of novel essential bacterial gene products Co-investigator 740,068 Research Grant
JE412668 (A) CD spectropolarimetry of proteins Principal Investigator 100,856 Research Grant
JE514287 (A) A cryoprobe for a 500MHz NMR spectrometer Co-investigator 100,000 Research Grant
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