Investigator / Supervisor details

NameProfessor Jean Manson
Current InstitutionUniversity of Edinburgh
Current DepartmentThe Roslin Institute
Institution websitehttp://www.ed.ac.uk
Previous InstitutionsThe Roslin Institute

Current Awards

ReferenceTitleAward RoleValue £Type
BBS/E/D/20002173 Pathogen diversity, host specificity and virulence Co-investigator 9,811,753 Institute Project

Completed Awards

ReferenceTitleAward RoleValue £Type
BB/C506356/1 Probing molecular mechanisms of neurodegenerative ageing in prion ablated mice Co-investigator 293,673 Research Grant
BB/C506356/2 Probing molecular mechanisms of neurodegenerative ageing in prion ablated mice Co-investigator 173,567 Research Grant
BB/C506356/3 Probing molecular mechanisms of neurodegenerative ageing in prion ablated mice Co-investigator 68,904 Research Grant
BB/D019141/1 The TSE Resource Centre - Continuation Principal Investigator 238,065 Research Grant
BB/D019141/2 The TSE Resource Centre - Continuation Principal Investigator 172,878 Research Grant
BB/D019141/3 The TSE Resource Centre - Continuation Principal Investigator 77,646 Research Grant
BB/G022666/1 The Roslin Institute TSE Resource Centre Principal Investigator 282,752 Research Grant
BB/L02635X/1 Animal Health Workhshop Principal Investigator 17,138 Research Grant
BBS/E/A/00001655 Investigating the role of glycosylation in the TSE's Principal Investigator 112,832 Institute Project
BBS/E/A/00001664 Strain typing of TSE strains Principal Investigator 35,588 Institute Project
BBS/E/A/00001665 The Role of Prp in Alzheimers Disease Principal Investigator 55,400 Institute Project
BBS/E/D/05241338 Protein misfolding in neurodegenerative disease Principal Investigator 1,057,714 Institute Project
BBS/E/D/05241339 Neuro-immune modelling Principal Investigator 1,405,126 Institute Project
BBS/E/D/05241340 Nature of TSE infection and Routes of Transmission Principal Investigator 2,489,591 Institute Project
BBS/E/D/05241341 The Healthy and Degenerating Neuron Principal Investigator 2,103,445 Institute Project
BBS/E/I/00000603 Scrapie strain variation and targeting in transgenic mice with glycosylation- deficient PrP Principal Investigator 7,259 Institute Project
BBS/E/I/00000604 A study of genes with altered expression in PrP-null mice to identify the function of PrP Principal Investigator 343,028 Institute Project
BBS/E/I/00000609 Study of mice with gene-targeted alterations of the PrP gene Principal Investigator 167,463 Institute Project
BBS/E/I/00000641 Do non-coding elements in the PrP gene affect incubation period or pathology of transmissible spongiform encephalopathies? Principal Investigator 152,577 Institute Project
BBS/E/I/00000642 Relationship between PrP gene dosage, scrapie agent replication and PrPSc accumulation Principal Investigator 53,161 Institute Project
BBS/E/I/00000647 Role of PrP in normal development & neurodegeneration in novel transgenic mice in which PrP gene expression is temporally & spatially controlled Principal Investigator 46,427 Institute Project
BBS/E/I/00000654 Development of mouse models for the study of human TSEs Principal Investigator 41,589 Institute Project
BBS/E/I/00000655 Membrane trafficking and expression of prion protein: their role in TSEs Principal Investigator 19,090 Institute Project
BBS/E/I/00000682 Alteration of TSE susceptibility defined by specific mutations in PrP Principal Investigator 500,320 Institute Project
BBS/E/I/00000683 Molecular characterisation of the pathogenesis of TSE infections Principal Investigator 2,810 Institute Project
BBS/E/I/00000814 Non-coding elements of the PrP gene and TSE susceptibility Principal Investigator 57,330 Institute Project
BBS/E/I/00000815 Relationship between PrP gene dosage, scrapie agent replication and PrPSc accumulation Principal Investigator 85,000 Institute Project
BBS/E/I/00000838 Investigation of transmissible spongiform encephalopathies using transgenic models Principal Investigator 39,130 Institute Project
BBS/E/I/00000865 The relative transmissibility of sheep and cattle BSE to humans Principal Investigator 37,807 Institute Project
BBS/E/I/00000972 Characterisation of strains of chronic wasting disease in North American cervids Principal Investigator 11,954 Institute Project
BBS/E/I/00000985 Gene targeted transgenic mice expressing human PrP as models for studying CJD Principal Investigator 2,668 Institute Project
BBS/E/I/00001001 Understanding the key events of TSE susceptibility and pathogenesis as a basis for disease intervention Principal Investigator 17,939 Institute Project
BBS/E/I/00001053 TSE core programme Principal Investigator 56,450 Institute Project
BBS/E/I/00001054 TSE Core programme Principal Investigator 1,654,893 Institute Project
BBS/E/I/00001153 Prevention, Control and Management of Prion Diseases Principal Investigator 76,055 Institute Project
BBS/E/I/00001180 Probing molecular mechamisms of neurodegenerative ageing of prion ablated mice Co-investigator 82,677 Institute Project
BBS/E/I/00001254 TSE Resource Centre Principal Investigator 20,745 Institute Project
BS204512 Study of mice with gene-targeted alterations to the PrP gene Co-investigator 437,661 Research Grant
BS204792 Scrapie strain variation and targeting in transgenic mice with glycosylation deficient PrP Principal Investigator 286,640 Research Grant
BS204795 A study of genes with altered expression in PrP null mice to identify the function of PrP Principal Investigator 133,848 Research Grant
BS205537 An investigation of neuronal properties synaptic function and plasticity in the brains of PrP-null and other PrP-mutant mice Co-investigator 129,229 Research Grant
BS308137 Membrane trafficking and expression of prion protein: their role in TSE Co-investigator 292,715 Research Grant
BS410547 Molecular characterisation of the pathogenesis of TSE infection Co-investigator 163,546 Research Grant
BS410573 Alterations in TSE susceptibility defined by specific mutations in PrP Principal Investigator 408,364 Research Grant
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