Investigator / Supervisor details

NameProfessor Christine Orengo
Current InstitutionUniversity College London
Current DepartmentStructural Molecular Biology
Institution websitehttp://www.ucl.ac.uk
Previous Institutions

Current Awards

ReferenceTitleAward RoleValue £Type
BB/S020039/1 Exploiting data driven computational approaches for understanding protein structure and function in InterPro and Pfam Principal Investigator 26,806 Research Grant
BB/V014722/1 Unlocking the chemical potential of plants: Predicting function from DNA sequence for complex enzyme superfamilies Principal Investigator 307,854 Research Grant
BB/W018802/1 Transforming the Structural Landscape of CATH to Aid Variant Analyses in Human and Agricultural Organisms and their Pathogens Principal Investigator 875,056 Research Grant
BB/X00306X/1 Novel Plastizymes: discovery and improvement of plastic-degrading enzymes by integrated cycles of computational and experimental approaches Co-investigator 3,024,438 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
00/B2/G/06275 Computational analysis of the human genome; from a protein structure/function perspective Co-Supervisor 37,091 Studentships
97/B1/E/03315 Consensus sequence/structure templates for homologous protein families Principal Supervisor 32,544 Studentships
98/B1/X/04329 Consensus 3D templates and contact maps for NMR structure determination Principal Supervisor 36,621 Studentships
99/B1/E/05269 Evolutionary analysis of protein structural families for assigning structure/function to genome sequences Principal Supervisor 35,156 Studentships
99/B1/X/05268 Comparative genomics incorporating 3D structural information Principal Supervisor 35,135 Studentships
APG16335 Capturing protein functional information from structural data: 3D templates and genome annotation Principal Investigator 120,022 Research Grant
B02058 Determinants and evolution of protein folds: sequence, structure and function relationships Co-investigator 155,735 Research Grant
B09684 Staff support for the computational resource in bioinformatics and structural biology at UCL Co-investigator 78,349 Research Grant
BB/C506264/1 Novel algorithms for gene expression time series Co-investigator 178,256 Research Grant
BB/C511748/1 High performance computing resources for structural biology and bioinformatics Principal Investigator 124,320 Research Grant
BB/D006392/1 Development and Dissemination of e-Protein: A distributed pipeline for proteome annotation using GRID technology Co-investigator 20,000 Research Grant
BB/E013201/1 Upgrade of Grid resources for Structural Bioinformatics Research in the Bloomsbury Centre for Bioinformatics Co-investigator 200,453 Research Grant
BB/F010451/1 An Integrated CATH Resource for the Postgenomic Era Principal Investigator 816,263 Research Grant
BB/H02364X/1 Exploiting High Performance Computing to Provide Functional Annotations via CATH-Gene3D Principal Investigator 108,971 Research Grant
BB/I025050/1 GENOME-3D: a UK network providing structure-based annotations for genotype to phenotype studies Principal Investigator 294,319 Research Grant
BB/K020013/1 An Greatly Expanded CATH-Gene3D with Functional Fingerprints to Characterise Proteins Principal Investigator 612,409 Research Grant
BB/L002817/1 A SPATIO-TEMPORAL MAP OF THE DEVELOPMENTAL FLY INTERACTOME Co-investigator 2,845,413 Research Grant
BB/L005026/1 Delivering ELIXIR-UK Co-investigator 30,857 Research Grant
BB/L007444/1 Metagenomics for new enzyme discovery and industrial biocatalysis Co-investigator 1,030,613 Research Grant
BB/M020088/1 CATH-FunL: Improving Gene Target Selection by Predicting Functional Modules in Biological Systems Principal Investigator 113,199 Research Grant
BB/N019253/1 Expanding Genome3D and disseminating the structural annotations via InterPro and PDBe Principal Investigator 386,521 Research Grant
BB/P023940/1 FunPDBe - Community driven enrichment of PDB data with structural and functional annotations Principal Investigator 104,716 Research Grant
BB/R009597/1 Leveraging functional profiling datasets with machine learning to uncover proteins and cellular processes important for ageing Co-investigator 779,213 Research Grant
BB/R014892/1 Increasing the Coverage and Accuracy of CATH for Comparative Genomics and Variant Interpretation Principal Investigator 621,216 Research Grant
BB/S016007/1 BBSRC-NSF/BIO Expanding the fold library in the twilight zone to facilitate structure determination of macromolecular machines Principal Investigator 344,149 Research Grant
BB/S020144/1 3D-Gateway - Gateway to protein structure and function Principal Investigator 293,276 Research Grant
BB/T002212/1 Mapping antibody class switch mechanisms and function Co-investigator 2,823,420 Research Grant
BB/T002735/1 SENSE - Screening of ENvironmental SEquences to discover novel protein functions, using informatics target selection and high-throughput validation Principal Investigator 229,346 Research Grant
BB/W003368/1 CATH-FunVar - Predicting Viral and Human Variants Affecting COVID-19 Susceptibility and Severity and Repurposing Therapeutics Principal Investigator 116,828 Research Grant
BBS/B/17220 ISPIDER - a pilot grid for integrative proteomics Co-investigator 202,883 Research Grant
BBS/S/P/2003/10379 Bioinformatics protocols to classify function in protein families and predict function in novel genes Principal Supervisor 44,773 Studentships
BEP17047 Structure-based function prediction using peer-to-peer distributed computing Co-investigator 190,196 Research Grant
BEP17048 A distributed pipeline for structure-based proteome annotation using GRID technology Co-investigator 378,836 Research Grant
BEP17056 Microarray analysis summer school Principal Investigator 31,600 Research Grant
BIF08767 Automated protein structure prediction using templates from the CATH structural database Principal Investigator 163,284 Research Grant
BIO10506 Bioinformatics to discover new animal and human pathogens and to predict virus gene function Co-investigator 185,416 Research Grant
BIO14300 Analysing virus gene expression data to understand regulatory interactions Co-investigator 140,176 Research Grant
BIO14453 Structural and functional annotation of genomes through dynamically optimised access to a distributed data warehouse Principal Investigator 67,324 Research Grant
BIO14463 Structural and functional Annotation of genomes through dynamically optimised access to a distributed data warehouse Co-investigator 65,356 Research Grant
BIO14465 Structural and functional annotation of genomes through dynamically optimised access to a distributed data warehouse Co-investigator 118,064 Research Grant
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