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Structural and functional annotation of genomes through dynamically optimised access to a distributed data warehouse

ReferenceBIO14453
Principal Investigator / Supervisor Professor Christine Orengo
Co-Investigators /
Co-Supervisors		 Professor Geoffrey Barton, Dr Nigel John Martin, Professor Alexandra Poulovassilis
Institution University College London
DepartmentStructural Molecular Biology
Funding typeResearch
Value (£) 67,324
StatusCompleted
TypeResearch Grant
Start date 01/02/2002
End date 31/07/2004
Duration30 months

Abstract

The challenge for the next decade will be to harness the wealth of protein sequence, structural and functional information being generated by the international genome initiatives, in order to reveal the molecular mechanisms of protein evolution, and the regulatory processes which control the observed phenotypes. Exploiting this genomic data will depend on building robust interfaces between the plethora of specialised databases being set up by experts in complementary areas of genome analysis. The structural data is essential for providing detailed insights into a protein's function, catalytic mechanism and interactions with other proteins. The project will develop data warehousing technology to enable an integrated view of primary structural data at the European Bioinformatics Institute (EBI) and derived data at UCL in order to provide extensive structural and functional data for the genomes. (Joint with grants 27/BIO14463 and 72/BIO14465).

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Bioinformatics (Phase 2) (BIO) [1998-2000]
Funding SchemeX – not Funded via a specific Funding Scheme
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