Investigator / Supervisor details

NameProfessor Jason Micklefield
Current InstitutionThe University of Manchester
Current DepartmentChemistry
Institution websitehttp://www.man.ac.uk
Previous Institutions

Current Awards

ReferenceTitleAward RoleValue £Type
BB/V008552/1 Antibiotic K16: Elucidation and Engineering Pathways to New Anti-infective Agents. Principal Investigator 486,550 Research Grant
BB/V016083/1 Methods for bioengineering NRPS/PKS assembly lines delivering peptide natural products with electrophilic warheads. Principal Investigator 470,912 Research Grant
BB/W014483/1 21EBTA: Engineering Biology with Synthetic Genomes (EBSynerGy) Co-investigator 1,329,012 Research Grant
BB/W019892/1 Advancing 'omics analysis with a Sciex ZenoToF 7600 mass spectrometer Co-investigator 712,101 Research Grant
BB/X002241/1 Engineering macrolactam antimicrobial agents (EMLA) Principal Investigator 521,507 Research Grant
BB/X008991/1 Methods for enzymatic synthesis of modified nucleic acids (MESNA) Principal Investigator 547,751 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
00/A4/B/06923 Modification of lipopeptide antibiotics from streptomyces by a chemical and genetic approach Principal Supervisor 37,126 Studentships
B12126 Combinatorial biosynthesis of lipopeptides: the function of the multienzyme system required for CDA biosynthesis Principal Investigator 192,320 Research Grant
B15998 Exploring the high affinity kinetically selective binding of RNA over DNA by pyrrolidine-amide oligonucleotide mimics (POM) Principal Investigator 207,632 Research Grant
BB/C008219/1 The Manchester Centre for Integrative Systems Biology (MCISB) Co-investigator 6,311,964 Research Grant
BB/C503662/1 Biosynthetic engineering of nonribosomal lipopeptide antibiotics in the model actinomycete Streptomyces coelicolor Principal Investigator 246,575 Research Grant
BB/C507210/1 Biosynthetic engineering of nonribosomal lipopeptide antibiotics in the model actinomycete Streptomyces coelicolor Co-investigator 213,808 Research Grant
BB/D005612/1 Co-evolution of small molecule responsive riboswitches Principal Investigator 688,480 Research Grant
BB/D017432/1 A novel strategy for microarrays of selective binding agents Co-investigator 590,475 Research Grant
BB/D524608/1 A high brilliance X-ray generator with CCD detector for the Manchester Interdisciplinary Biocentre Co-investigator 199,800 Research Grant
BB/E013007/1 A Biological Pulsed EPR/ENDOR Facility for the Manchester Interdisciplinary Biocentre Co-investigator 240,000 Research Grant
BB/E017010/1 Substrate channelling in catabolism of methylated amines Co-investigator 681,729 Research Grant
BB/F000537/1 Dynamically-coupled enzyme catalysis: towards a step change in our understanding of enzyme catalysed reactions Co-investigator 2,402,423 Research Grant
BB/H015868/1 Bbsrc tp bio processing bid 2009 Co-investigator 75,281 Training Grants
BB/H015914/1 A synthetic biology approach for engineering the biosynthesis of new friulimicin lipopeptide antibiotics Principal Investigator 75,281 Training Grants
BB/I008055/1 Bioorthogonal site-selective protein immobilisation and labelling Principal Investigator 475,116 Research Grant
BB/I012648/1 Orthogonal riboswitches as tools for controlling gene expression in bacteria Principal Investigator 639,275 Research Grant
BB/I020764/1 Directed Evolution of Enantiocomplementary Malonate Decarboxylases. Principal Investigator 317,821 Research Grant
BB/J019089/1 Feasibility and Benchmarking of RiboTite gene expression control technology Principal Investigator 146,160 Research Grant
BB/K00199X/1 Rapid Evolution of Enzymes and Synthetic Micro-organisms for the Development of Industrial Biocatalysts Co-investigator 3,604,052 Research Grant
BB/K002341/1 Exploiting natural product assembly line genomics and synthetic biology for discovery and optimisation of novel agrochemicals Co-investigator 3,552,007 Research Grant
BB/L002299/1 Bioengineering of next generation lipoglycopeptide antibiotics Principal Investigator 690,996 Research Grant
BB/L013754/1 NATURAL PRODUCTS DISCOVERY AND BIOENGINEERING NETWORK (NPRONET) Principal Investigator 506,944 Research Grant
BB/L014823/1 Multi-purpose instrument for advanced Raman spectroscopy techniques Co-investigator 409,322 Research Grant
BB/M011658/1 An advanced multi-purpose instrument for biological ultrafast time resolved spectroscopy Co-investigator 491,200 Research Grant
BB/M017702/1 CENTRE FOR SYNTHETIC BIOLOGY OF FINE AND SPECIALITY CHEMICALS Co-investigator 10,198,943 Research Grant
BB/N023536/1 A Synthetic Biology Approach for the Total Biosynthesis of Semi-Synthetic Antibiotics Principal Investigator 1,168,602 Research Grant
BB/R000069/1 High-throughput micro-fermentation for directed evolution and strain selection in industrial biotechnology Co-investigator 214,394 Research Grant
BB/R000093/1 MultiUSer equipment for high-throughput, high-content analysis in Industrial and Cellular biotechnology (MUSIC) Co-investigator 277,784 Research Grant
BB/R01034X/1 Exploiting Halogenase Enzymes: New Reaction Pathways via Enzymatic CH Activation Principal Investigator 1,000,545 Research Grant
BB/R013497/1 A versatile proton transfer reaction-mass spectrometry platform for online monitoring of VOCs. Co-investigator 453,088 Research Grant
BB/R505882/1 Chemoenzymatic cascades for one carbon functionalization of pharmaceutical scaffolds Principal Investigator 98,212 Training Grants
BBS/OS/GC/4020014881 The BBSRC GCRF Workshop Grant Principal Investigator 20,000 Research Grant
BBS/S/E/2006/13267 Chemical and genetic selection of small molecule responsive riboswitches Principal Supervisor 69,212 Studentships
BBS/S/M/2003/10492 Development of methodology for engineering the biosynthesis of non-ribosomal peptides in Streptomyces coelicolor Principal Supervisor 44,695 Studentships
REI20500 Infrastructure for single-molecule biology in the Manchester interdisciplinary biocentre Co-investigator 113,120 Research Grant
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