Investigator / Supervisor details

NameProfessor Dek Woolfson
Current InstitutionUniversity of Bristol
Current DepartmentChemistry
Institution websitehttp://www.bris.ac.uk
Previous InstitutionsUniversity of Sussex

Current Awards

ReferenceTitleAward RoleValue £Type
BB/R00661X/1 Rational computational protein design in ISAMBARD: new approaches, folds and functions Principal Investigator 896,705 Research Grant
BB/S002820/1 Design and in vivo assembly of switchable protein-protein interactions for transcription regulation Co-investigator 730,853 Research Grant
BB/T020105/1 CuPiD: A European Network in Computational Protein Design Principal Investigator 30,612 Research Grant
BB/V004220/1 19-BBSRC-NSF/BIO. Leveraging synthetic biology to probe the rules of cell morphogenesis. Principal Investigator 805,498 Research Grant
BB/V006231/1 Coiled-coil Technology for Regulating Intracellular Protein-protein Interactions Principal Investigator 440,228 Research Grant
BB/W005581/1 Mechanism and design of a pH sensor at the organelle-cytoskeleton interface Co-investigator 788,527 Research Grant
BB/W013959/1 BrisEngBio: From Synthetic to Engineering Biology at Bristol Principal Investigator 1,517,913 Research Grant
BB/X003027/1 Generalised Photocatalysis by Enzymes (GENPENZ) Co-investigator 3,178,051 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
01/B1/E/07465 Novel peptide-synthetic polymer hybrids for fabricating nanoscale fibres and tubes Principal Supervisor 39,359 Studentships
02/B1/E/08406 Design, characterisation and development of self-assembling peptide nanotubes Principal Supervisor 41,845 Studentships
95/A1/B/00497 The development of methods to aid the design of new proteins Principal Supervisor 34,171 Studentships
96/B1/B/02541 The rational design of a protein with a prescribed structure Principal Supervisor 31,607 Studentships
98/A2/B/04537 The stability and specificity of coiled-coil protein-protein interactions Principal Supervisor 33,706 Studentships
B04756 Design of proteins of prescribed structure: core-directed protein design Principal Investigator 143,746 Research Grant
B10280 The characterisation and development of peptides designed to switch structural state Principal Investigator 160,823 Research Grant
B17958 Systematic analysis of how sequence affects alpha- to-beta structural switching in a straightforward designed peptide system Principal Investigator 226,672 Research Grant
B17958/2 Systematic analysis of how sequence affects alpha- to-beta structural switching in a straightforward designed peptide system Principal Investigator 31,127 Research Grant
B19078 Engineering novel protein-ligand interactions Co-investigator 184,144 Research Grant
BB/D003016/1 Towards better predictions designs and engineering of coiled-coil protein-protein interactions Principal Investigator 225,331 Research Grant
BB/E022359/1 Decorating self-assembled nano-to-mesoscale peptide fibres with functional proteins and protein complexes Principal Investigator 569,624 Research Grant
BB/F007256/1 Structure function and mechanics of the Moraxella catarrhalis adhesin UspA1 Co-investigator 490,930 Research Grant
BB/F011199/1 Optical spectroscopy for biomolecular interactions Co-investigator 95,974 Research Grant
BB/F01872X/1 Synthetic Components Network: Towards Synthetic Biology From The Bottom Up Principal Investigator 125,833 Research Grant
BB/G008833/1 A biomolecular-design approach in synthetic biology: towards synthetic cytoskeletons Principal Investigator 673,294 Research Grant
BB/H01716X/1 Alpha-helical peptide hydrogels as instructive scaffolds for 3D cell culture and tissue engineering Principal Investigator 659,988 Research Grant
BB/J008990/1 Hexaporins: the rational design of transmembrane channels Principal Investigator 439,297 Research Grant
BB/L010518/1 SAGEs: Self-assembled peptide-based cages for the presentation, encapsulation and delivery of bioactive molecules to cells in culture Principal Investigator 731,565 Research Grant
BB/L01386X/1 BrisSynBio: Bristol Centre for Synthetic Biology Principal Investigator 13,528,180 Research Grant
BB/L014181/1 Photo-oxidation and cryofluorescence for Correlative Light Electron Microscopy. Co-investigator 643,781 Research Grant
BB/M002969/1 Development of supramolecular assemblies for enhancing cellular productivity and the synthesis of fine chemicals and biotherapeutics. Co-investigator 3,484,653 Research Grant
BB/M005615/1 14-ERASynBio: BioMolecular Origami Principal Investigator 333,189 Research Grant
BB/P025617/1 BrisSynBio - MaxSynBio: Building a minimal biology Co-investigator 10,081 Research Grant
BB/R000484/1 BlueCryo Image Processing Computing Cluster Co-investigator 300,000 Research Grant
BB/R01387X/1 Life in 3D, expanding the structural length scales via Serial Block Face Scanning Electron Microscopy (SBF-SEM) Co-investigator 600,000 Research Grant
BB/T017597/1 Super-resolution imaging Co-investigator 569,994 Research Grant
BBS/B/04676 Exploring the nanoscale structure and assembly of a designed protein fibre Principal Investigator 196,925 Research Grant
BBS/B/04676/2 Exploring the nanoscale structure and assembly of a designed protein fibre Principal Investigator 124,240 Research Grant
E13753 Nanofabrication of protein fibres and matrices using self-assembly peptides of De Novo design Principal Investigator 208,488 Research Grant
E20126 Combining stem cells self-assembling-peptide scaffolds and novel bioreactors in cartilage engineering Principal Investigator 112,528 Research Grant
E20126/2 Combining stem cells self-assembling-peptide scaffolds and novel bioreactors in cartilage engineering Principal Investigator 78,973 Research Grant
JE616384 An atomic force microscopy facility for imaging biopolymers and macromolecular assemblies at Sussex Principal Investigator 108,188 Research Grant
JE616389 Facility for the kinetic analysis of protein function folding and stability Co-investigator 71,168 Research Grant
JEI09469 Establishment of an analytical-ultra centrifuge facility for studies of protein-protein interactions Principal Investigator 95,000 Research Grant
REI20503 Linear dichroism for realtime small volume analysis of biomacromolecule structure and ligand binding Co-investigator 66,700 Research Grant
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