Award details

An atomic force microscopy facility for imaging biopolymers and macromolecular assemblies at Sussex

Reference	JE616384
Principal Investigator / Supervisor	Professor Dek Woolfson
Co-Investigators / Co-Supervisors	Professor Steven Armes, Professor Alan Lehmann
Institution	University of Sussex
Department	Biology and Environmental Science
Funding type	Research
Value (£)	108,188
Status	Completed
Type	Research Grant
Start date	03/05/2002
End date	03/05/2003
Duration	12 months

Abstract

Imaging surface topography using Atomic Force Microscopy (AFM) is becoming an essential technique for research in the biological and nano-scale sciences. We aim to establish an AFM facility within the new Centre for Advanced Microscopy in the School of Biological Sciences at Sussex. The Centre will also house existing EM facilities and new light microscopes. The resulting suite will provide a focal point for a wide variety of Sussex scientists and their collaborators interested in nano-scale science and imaging. This application focuses on multi-disciplinary research from three well-established groupings, namely protein design, synthetic polymer chemistry and DNA damage and repair. The work described reflects (1) our current needs for AFM in the area of molecular self-assembly and nanotechnology; in particular, the characterisation of designed peptide fibres and synthetic micelles, nanocomposites and biocompatible polymer coatings. (2) In addition to developing applications in nanotechnology, our medium-to- long term ambitions include making the facility available to our world-leading cell biologist and so explore structural and biophysical approaches in these fields; specifically, this application describes research from the new Genome Damage and Stability Centre, whose interests include characterising a range of protein-DNA complexes associated with DNA damage and repair.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Initiative 2001 (JE6) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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