BBSRC Portfolio Analyser

Investigator / Supervisor details

NameProfessor Andrew Munro
Current InstitutionThe University of Manchester
Current DepartmentChemistry
Institution websitehttp://www.man.ac.uk
Previous InstitutionsUniversity of Leicester

Current Awards

No current BBSRC awards

Completed Awards

ReferenceTitleAward RoleValue £Type
02/A2/C/08171 Defining structure and mechanism in Mycobacterium tuberculosis redox systems Co-Supervisor 41,845 Studentships
02/B1/C/08176 Mechanistic enzymology of unique P450s in the tuberculosis and leprosy pathogens Co-Supervisor 41,845 Studentships
B12703 Chemistry and function of the active site of P450 BM3 probed by resonance Raman and surface enhanced resonance Raman scattering Co-investigator 217,136 Research Grant
B16808 Deconvoluting the electron transfer pathway in flavocytochrome P450 BM3 Principal Investigator 200,428 Research Grant
BB/C00390X/1 Mechanistic basis of uphill electron transfer and reductive methylation in the human MS¿MSR electron transfer complex Co-investigator 237,482 Research Grant
BB/C00390X/2 Mechanistic basis of uphill electron transfer and reductive methylation in the human MSMSR electron transfer complex Co-investigator 185,304 Research Grant
BB/C006879/1 Construction of a biotechnologically versatile and stable oxygenase biocatalyst Principal Investigator 209,305 Research Grant
BB/C006879/2 Construction of a biotechnologically versatile and stable oxygenase biocatalyst Principal Investigator 193,248 Research Grant
BB/C008294/1 Elucidating the role of radical chemistry in the mechanism of action of monoamine oxidase. Co-investigator 276,756 Research Grant
BB/C511305/1 Computing infrastructure to underpin integrated and predictive structural and systems biology Co-investigator 100,611 Research Grant
BB/D524608/1 A high brilliance X-ray generator with CCD detector for the Manchester Interdisciplinary Biocentre Co-investigator 199,800 Research Grant
BB/E010717/1 A generic biocatalytic reaction platform for the stereospecific reduction and oxidation of alkenes Co-investigator 1,704,123 Research Grant
BB/E013007/1 A Biological Pulsed EPR/ENDOR Facility for the Manchester Interdisciplinary Biocentre Co-investigator 240,000 Research Grant
BB/F002521/1 Novel routes to catalytic intermediates in the cytochrome P450 catalytic cycle Principal Investigator 520,651 Research Grant
BB/F004397/1 Reflection anisotropy spectroscopy as a new tool for linking macromolecular conformation to biological function: applications in biological redox chem Co-investigator 354,969 Research Grant
BB/F00883X/1 Directed evolution approaches to generation of an industrially applicable biocatalyst Principal Investigator 587,704 Research Grant
BB/F014252/1 Functional and structural characterization of a novel heme- and micro RNA-binding human protein Principal Investigator 688,614 Research Grant
BB/G008558/1 A novel regulator of human apoptosis Principal Investigator 548,111 Research Grant
BB/G014329/1 Characterization of a superior biocatalyst for pravastatin production Principal Investigator 332,908 Research Grant
BB/G016968/1 Evolution of efficient p450 biocatalysts for human drug metabolite production Principal Investigator 74,410 Training Grants
BB/H006265/1 Elucidating and exploiting cytochrome P450 TxtE-catalysed tryptophan nitration in thaxtomin phytotoxin biosynthesis Principal Investigator 17,505 Research Grant
BB/I016082/1 Flavocytochrome P450 BM3 engineering for scalable P450 reactions Principal Investigator 91,932 Training Grants
BB/I019227/1 A fragment based screening approach to rationalizing M. tuberculosis P450 molecular selectivity Principal Investigator 411,571 Research Grant
BB/I020160/1 Structure and mechanism of a key enzyme in M. tuberculosis cell envelope biogenesis Principal Investigator 391,575 Research Grant
BB/J012645/1 Characterization of P450 oxidases catalysing alkane/alkene production for Bioenergy applications Principal Investigator 92,173 Training Grants
BB/K001884/1 Molecular reconstruction of flavocytochrome P450 BM3 Principal Investigator 436,345 Research Grant
BB/K012282/1 Structure-led engineering of a biotechnologically important biocatalyst Principal Investigator 93,520 Training Grants
BB/K017802/1 In vivo alpha-olefin production: a sustainable hydrocarbon source Co-investigator 606,412 Research Grant
BB/L014823/1 Multi-purpose instrument for advanced Raman spectroscopy techniques Co-investigator 409,322 Research Grant
BB/L015048/1 Hydrogen/Deuterium Exchange and Ion Mobility Mass Spectrometry to Underpin Research on Protein Interactions Co-investigator 498,947 Research Grant
BB/L017253/1 High value oxy-pharmaceuticals from P450 BM3 "gatekeeper" variants Principal Investigator 94,126 Training Grants
BB/M011658/1 An advanced multi-purpose instrument for biological ultrafast time resolved spectroscopy Co-investigator 491,200 Research Grant
BB/M016986/1 Synthetic biology applications of P450 BM3 Principal Investigator 95,042 Training Grants
BB/M017702/1 CENTRE FOR SYNTHETIC BIOLOGY OF FINE AND SPECIALITY CHEMICALS Co-investigator 10,198,943 Research Grant
BB/N006275/1 Molecular mechanism and engineering of P450 peroxygenases for synthetic biology applications Principal Investigator 462,081 Research Grant
BB/P000622/1 Exploring the biotechnological potential of the UbiD (de)carboxylase family: novel biochemistry for renewable commodity chemicals Co-investigator 585,505 Research Grant
BB/P010180/1 Interrogation of the catalytic properties of MhuD - a crucial heme oxygenase in Mycobacterium tuberculosis Principal Investigator 448,944 Research Grant
BB/P504920/1 Substrate dependent evolution of Cytochromes P450 in determining species sensitivity to xenobiotics Advances in biosciences sustainable innovations Principal Investigator 96,696 Training Grants
BB/R000069/1 High-throughput micro-fermentation for directed evolution and strain selection in industrial biotechnology Co-investigator 214,394 Research Grant
BB/R009961/1 Construction of potent and specific inhibitors of M. tuberculosis redox enzymes using fragment screening methods Principal Investigator 418,298 Research Grant
BB/R013497/1 A versatile proton transfer reaction-mass spectrometry platform for online monitoring of VOCs. Co-investigator 453,088 Research Grant
BB/R505870/1 Addressing antimicrobial resistance in Mycobacterium tuberculosis using a fragment screening led approach Principal Investigator 98,212 Training Grants
BB/T017473/1 A nanosecond laser spectroscopy platform for studying light-activated biomolecules Co-investigator 338,507 Research Grant
BB/T017643/1 Glacios cryo-electron microscope for single particle analysis and electron tomography of proteins, complexes and fibrillar assemblies Co-investigator 750,000 Research Grant
BBS/B/06288 Molecular enzymology of FprA - a pivotal enzyme in M. tuberculosis redox chemistry Principal Investigator 207,930 Research Grant
BBS/B/06288/2 Molecular enzymology of FprA - a pivotal enzyme in M. tuberculosis redox chemistry Principal Investigator 116,783 Research Grant
BBS/B/1311X Conformational equilibria and electron transfer in NADPH-cytochrome P450 reductase Co-investigator 223,004 Research Grant
BBS/S/B/2003/12732 Mechanistic analysis of nitric oxide synthase Principal Supervisor 17,317 Studentships
BBS/S/H/2005/11980 Enzymology of the human apoptosis-inducing flavoprotein AMID: A chemical genetics approach Principal Supervisor 49,864 Studentships
BBS/S/L/2003/10211 Mechanistic analysis of nitric oxide synthase Principal Supervisor 27,786 Studentships
C15314 Structure and function of sterol demethylases from Mycobacterium tuberculosis and Streptomyces coelicolor Principal Investigator 147,392 Research Grant
C16349 Electron transfer in dihydroorotate dehydrogenase B: a novel flavoprotein and antimicrobial target Co-investigator 191,652 Research Grant
C18194 Radical reappraisal of the mechanism of electron transfer and the role of calmodulin in nitric synthase Co-investigator 171,568 Research Grant
C18194/2 Radical reappraisal of the mechanism of electron transfer and the role of calmodulin in nitric synthase Co-investigator 26,388 Research Grant
C19031 Elucidating factors controlling enzymic H-tunnelling through structural and kinetic studies of dimethylglycine oxidase Co-investigator 190,784 Research Grant
C19031/2 Elucidating factors controlling enzymic H-tunnelling through structural and kinetic studies of dimethylglycine oxidase Co-investigator 72,367 Research Grant
C19757 Elucidating enzyme mechanism and physiological role of a key P450 enzyme (CYP121) from mycobacterium tuberculosis Principal Investigator 196,872 Research Grant
C19757/2 Elucidating enzyme mechanism and physiological role of a key P450 enzyme (CYP121) from mycobacterium tuberculosis Principal Investigator 86,688 Research Grant
E20186 Industrial biocatalysts by design: rational re-engineering of flavocytochrome p450 BM3 for chiral chemical synthesis Co-investigator 243,929 Research Grant
REI20488 Isothermal titration calorimetry: novel and established applicatons in redox enzymology Co-investigator 29,252 Research Grant
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