Investigator / Supervisor details

NameProfessor Alan Dickson
Current InstitutionThe University of Manchester
Current DepartmentChem Eng and Analytical Science
Institution websitehttp://www.man.ac.uk
Previous Institutions

Current Awards

ReferenceTitleAward RoleValue £Type
BB/W019779/1 Integrated bioreactor platform for rapid scale-up and translation Co-investigator 553,682 Research Grant
BB/W019892/1 Advancing 'omics analysis with a Sciex ZenoToF 7600 mass spectrometer Co-investigator 712,101 Research Grant
BB/W510282/1 Building and commercialisation of a new mammalian cell factory platform Principal Investigator 103,929 Training Grants
BB/X512205/1 SELECT EXpress Principal Investigator 178,176 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
00/A1/B/06157 NMR-derived structure determinations; beyond NOEs Principal Supervisor 37,132 Studentships
01/A2/S/07300 Molecular events that promote dedifferentiation during hepatocyte isolation and culture Principal Supervisor 39,315 Studentships
01/B1/C/07162 The study of the interaction between proteins of the complement system using NMR and other methods Principal Supervisor 39,669 Studentships
95/A1/B/00206 Chemical synthesis and structure determination of viral receptors Principal Supervisor 30,553 Studentships
96/A2/E/02349 Novel approaches for rational design of fed-batch processes Principal Supervisor 31,585 Studentships
96/B1/G/02356 Maintenance of liver cell phenotype: optimisation for drug metabolism and toxicity studies Principal Supervisor 31,585 Studentships
97/A2/G/03331 Regulation of recombinant protein expression Principal Supervisor 32,537 Studentships
97/B1/B/03169 Viral mimics for design of anti-inflammatory therapeutics Principal Supervisor 32,558 Studentships
98/A1/B/04163 Structure of cell-surface viral targets Principal Supervisor 33,602 Studentships
98/A2/C/04347 Stress-activated protein kinases and control of hepatocyte differentiation Principal Supervisor 33,602 Studentships
99/A2/E/05293 Optimisation of recombinant protein expression Principal Supervisor 35,156 Studentships
BB/D009375/1 Towards the manipulation of the UPR in mammalian cells to orchestrate cellular re-organization for enhanced monoclonal antibody production Co-investigator 288,003 Research Grant
BB/E005985/1 Application of metabolomics profiling of recombinant mammalian cells to bioprocess design Principal Investigator 768,110 Research Grant
BB/E013155/1 Systematic small molecule analysis using GC-MS Co-investigator 142,366 Research Grant
BB/E527355/1 Masters (MRes) in Biological Sciences Principal Investigator 839,040 Training Grants
BB/E528579/1 BBSRC Industrial Partnership Grant Principal Investigator 70,820 Training Grants
BB/G010250/1 Raman spectroscopy as a novel analytical bioprocessing tool for PAT Co-investigator 401,725 Research Grant
BB/G529932/1 BBSRC Industrial CASE Partnership Grant Principal Investigator 72,540 Training Grants
BB/H015868/1 Bbsrc tp bio processing bid 2009 Co-investigator 75,281 Training Grants
BB/I010610/1 De novo sequencing of the Chinese Hamster Ovary (CHO) cell genome Co-investigator 85,120 Research Grant
BB/I017186/1 Predictable Protein Production Co-investigator 655,645 Research Grant
BB/I017194/1 Understanding and predicting aggregation in biopharmaceuticals Co-investigator 579,057 Research Grant
BB/J003883/1 Protein burden in protein overproduction Co-investigator 95,932 Training Grants
BB/K011170/1 Application of single cell metabolite profiling to optimisation of stem cell bioprocessing Principal Investigator 451,412 Research Grant
BB/K020838/1 Enhancing recombinant protein secretion and quality in CHO cell bioprocessing Principal Investigator 93,520 Training Grants
BB/K020978/1 Development of high density CHO cell culture manufacturing systems Principal Investigator 93,520 Training Grants
BB/K501244/1 Difficult to Express Soluble Proteins. Why are some soluble recombinant proteins difficult to express even in mammalian cells and how do we fix it? Principal Investigator 92,173 Training Grants
BB/L013770/1 Bioprocessing Network: BioProNET Co-investigator 811,631 Research Grant
BB/L014823/1 Multi-purpose instrument for advanced Raman spectroscopy techniques Co-investigator 409,322 Research Grant
BB/M001164/1 13 ERA IB: Investigating NOvel VAluable bio-Therapeutics and Expression systems Principal Investigator 288,078 Research Grant
BB/M01701X/1 Combinatorial genome editing to create enhanced biomanufacturing platforms Principal Investigator 426,837 Research Grant
BB/N004000/1 Integration of academic perspective into the scale-up of CHO cell bioprocessing: Manufacturing understanding Principal Investigator 113,943 Research Grant
BB/N022041/1 Cuba: Application of 'omics in the metabolic study of high cell density continuous cell cultures of recombinant NS0 myeloma cell lines Principal Investigator 19,717 Research Grant
BB/P004237/1 Production of difficult to express essential bacterial proteins Principal Investigator 108,007 Research Grant
BB/P004296/1 Bioprocessing Skills School: Embedding the industrial perspective Principal Investigator 90,700 Training Grants
BB/P504336/1 Understanding the role of C Terminal Lysine in protein Lysine in protein secretory pathways Principal Investigator 96,696 Training Grants
BB/R000069/1 High-throughput micro-fermentation for directed evolution and strain selection in industrial biotechnology Co-investigator 214,394 Research Grant
BB/R000093/1 MultiUSer equipment for high-throughput, high-content analysis in Industrial and Cellular biotechnology (MUSIC) Co-investigator 277,784 Research Grant
BB/R002096/1 An integrated cell and protein engineering approach to generate enhanced CHO cell platforms for manufacture of difficult to express biopharmaceuticals Principal Investigator 371,346 Research Grant
BB/R013497/1 A versatile proton transfer reaction-mass spectrometry platform for online monitoring of VOCs. Co-investigator 453,088 Research Grant
BB/R505705/1 Autophagy and multi-vesicular body trafficking in HEK293 cells during the production of lentivirus-ike virions by over expression of GagPo1 Principal Investigator 98,212 Training Grants
BBS/S/C/2002/12892 Optimisation of recombinant protein expression in mammalian cell lines (Funded via Training Grant BB/A517677/1) Principal Supervisor Studentships
BBS/S/D/2003/12750 Stability of protein expression in recombinant mammalian cell lines (Funded via Training Grant BB/A517677/1) Principal Supervisor Studentships
C11212 The dynamics of mitosis the cytoskeleton membrane trafficking and protein expression in microbes and mammalian cells Co-investigator 94,441 Research Grant
E18788 Mechamisms underlying stability/instability of industrially-relevant recombinant mammalian cells Principal Investigator 274,548 Research Grant
G06311 Maintenance of liver cell phenotype: characterisation of signalling factors which regulate differentiation of isolated hepatocytes Principal Investigator 218,850 Research Grant
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