Investigator / Supervisor details

NameProfessor Florian Hollfelder
Current InstitutionUniversity of Cambridge
Current DepartmentBiochemistry
Institution websitehttp://www.cam.ac.uk
Previous Institutions

Current Awards

ReferenceTitleAward RoleValue £Type
BB/W000504/1 Mapping the overlapping fitness landscapes of a superfamily of promiscuous enzymes: strategies for directed evolution? Principal Investigator 604,002 Research Grant
BB/W006391/1 CAZyme evolution and discovery: Ultrahigh throughput screening of carbohydrate-active enzymes in modular assays modular based on coupled reactions Principal Investigator 463,891 Research Grant
BB/X00306X/1 Novel Plastizymes: discovery and improvement of plastic-degrading enzymes by integrated cycles of computational and experimental approaches Principal Investigator 3,024,438 Research Grant

Completed Awards

ReferenceTitleAward RoleValue £Type
B15990 Directed evolution guided by catalytic promiscuity Principal Investigator 188,932 Research Grant
BB/C511313/1 Quantative assessment of molecular recognition events by isothermal titration calorimetry Principal Investigator 42,438 Research Grant
BB/D014964/1 Systematic Identification of Tunable Transfection Reagents for Stem Cell Biology Principal Investigator 382,733 Research Grant
BB/D524824/1 Ion-trap mass spectrometry for integrative biology Co-investigator 133,230 Research Grant
BB/I004327/1 Catalytic promiscuity in a protein superfamily Principal Investigator 459,467 Research Grant
BB/I016589/1 Directed evolution of therapeutic enzymes as alternatives to antibodies Principal Investigator 91,932 Training Grants
BB/J008214/1 Exploring the Potential of Networked Directed Evolution Based on Novel LacI/effector Pairs Principal Investigator 324,256 Research Grant
BB/K012665/1 Continuous directed evolution for the study of intracellular biomolecules Principal Investigator 93,520 Training Grants
BB/K013629/1 New detection modes for droplet microfluidics Principal Investigator 87,811 Research Grant
BB/L002469/1 Towards Novel Glycoside Hydrolases Principal Investigator 361,382 Research Grant
BB/L502248/1 High-throughput droplet based screening of enzyme libraries Principal Investigator 93,520 Training Grants
BB/M016692/1 Protein Engineering by Phenotypic Screening in Microfluidic Droplets Principal Investigator 95,042 Training Grants
BB/R505055/1 Using Phenotypic Screening in Microfluidic Droplets to Probe and Perturb Cellular Functions Principal Investigator 96,696 Training Grants
BB/T003545/1 SENSE - Screening of ENvironmental SEquences to discover novel protein functions using informatics target selection and high-throughput validation Principal Investigator 395,970 Research Grant
BB/V018973/1 High throughput gentle imaging of cells, embryos and organoids with an inverted lattice light sheet microscope. Co-investigator 698,549 Research Grant
BBS/S/C/2004/12901 A new genotype-phenotype linkage for directed evolution (Funded via Training Grant BB/A517685/1) Principal Supervisor Studentships
BBS/S/D/2003/12748 New oligo-and polyvalent reagents for non-viral gene therapy (Funded via Training Grant BB/A517685/1) Principal Supervisor Studentships
C19399 Prediction generation and assessment of high- throughput protein-protein interaction data Principal Investigator 153,152 Research Grant
G20017 Probing histone acetyl transferase function by directed evolution Principal Investigator 201,956 Research Grant
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