Award details

An evaluation of the bioavailability of food riboflavin and the modulating effects of genotype on riboflavin function

Reference	D19616
Principal Investigator / Supervisor	Mr Paul Finglas
Co-Investigators / Co-Supervisors	Dr Jack Dainty
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	26,208
Status	Completed
Type	Research Grant
Start date	01/10/2003
End date	30/09/2006
Duration	36 months

Abstract

Recent national surveys in the UK have highlighted an increasing prevalence of biochemical ariboflavinosis but a discrepancy with estimated riboflavin intakes. This study aims to quantify riboflavin bioavailability from foods and to develop a mathematical model of absorption; also to evaluate the modulating effects of common polymorphisms in genes encoding for riboflavin dependent enzymes on the relationship between dietary intake and functional riboflavin status. The pharmacokinetics of riboflavin absorption from food will be studied in humans using stable isotope methodology. The modulating effects of relevant common polymorphisms on intake/function relationships will be carried out in a controlled randomised human intervention study. (Joint with grant number 19615).

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

D19615 An evaluation of the bioavailability of food riboflavin and the modulation effects of genotype on riboflavin function

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search