Award details

An evaluation of the bioavailability of food riboflavin and the modulation effects of genotype on riboflavin function

Reference	D19615
Principal Investigator / Supervisor	Professor Hilary Powers
Co-Investigators / Co-Supervisors	Dr Michael Barker
Institution	University of Sheffield
Department	Division of Clinical Sciences North
Funding type	Research
Value (£)	192,560
Status	Completed
Type	Research Grant
Start date	17/11/2003
End date	16/01/2007
Duration	38 months

Abstract

Recent national surveys in the UK have highlighted an increasing prevalence of biochemical ariboflavinosis but a discrepancy with estimated riboflavin intakes. This study aims to quantify riboflavin bioavailability from foods and to develop a mathematical model of absorption, also to evaluate the modulating effects of common polymorphisms in genes encoding for riboflavin dependent enzymes on the relationship between dietary intake and functional riboflavin status. The pharmacokinetics of riboflavin absorption from food will be studied in humans using stable isotope methodology. The modulating effects of relevant common polymorphisms on intake/function relationships will be carried out in a controlled randomised human intervention study. (Joint with grant number 19616).

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

D19616 An evaluation of the bioavailability of food riboflavin and the modulating effects of genotype on riboflavin function

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search