BBSRC Portfolio Analyser

Award details

Cambridge and East Anglia Centre: The Structural Biology of cell signalling in animals plants and microbes

ReferenceSB11271
Principal Investigator / Supervisor Professor Sir Tom Blundell
Co-Investigators /
Co-Supervisors
Institution University of Cambridge
DepartmentBiochemistry
Funding typeResearch
Value (£) 710,811
StatusCompleted
TypeResearch Grant
Start date 01/02/2000
End date 01/04/2005
Duration62 months

Abstract

The objective is to study the structural biology of signalling, including receptor activation at the cell surface, and signal transduction in the cytoplasm, leading to control of transcription. These processes involve multicomponent complexes, some of which are stable and others transient. We will study the structures of microbial, plant and mammalian systems, with a view to comparative analyses. We propose the establishment of linked laboratories in microbial, animal and plant protein expression and preparation, nuclear magnetic resonance, protein crystallography, mass spectroscopy, microcalorimetry and computing, exploiting strengths and bringing to critical mass expertise in structural and cell biology at Cambridge University, University of East Anglia, John Innes Centre and Babraham Institute. (Joint with grants SB11272, SB11274 and SB11275).

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Structural Biology (SB) [1997-1998]
Funding SchemeX – not Funded via a specific Funding Scheme
terms and conditions of use (opens in new window)
export PDF file
back to list new search