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The nutritional basis of the periparturient relaxation of immunity to gastrointestinal parasites

Reference	S13807
Principal Investigator / Supervisor	Professor Ilias Kyriazakis
Co-Investigators / Co-Supervisors	Dr Robert Coop
Institution	SRUC
Department	Department of Animal Nutrition and Healt
Funding type	Research
Value (£)	244,344
Status	Completed
Type	Research Grant
Start date	01/11/2000
End date	01/11/2003
Duration	36 months

Abstract

The overall objective of the work is to address the hypothesis that the occurrence and magnitude of the periparturient relaxation of immunity (PPRI) to gastrointestinal parasites in ewes is sensitive to nutrient supply. Our specific objectives are : 1) to test the effect of protein supply on the occurrence and magnitude of PPRI to Ostertagia circumcincta; 2) to investigate the effect of protein supply and the intensity of the reproductive effort on the temporal development and magnitude of PPRI; 3) to investigate the role of maternal, particularly protein, reserves on the occurrence and magnitude of PPRI; 4) to address the selective effect of nutrition on the separate effector mechanisms of the immune response to gastrointestinal parasites. The quantitative information generated from above will be used to 5) develop a framework that accounts quantitatively for the effects of host nutrition on the expression of immunity to O. circumcincta in periparturient ewes.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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