Award details

Relationship between cell cycle control parental imprinting and seed development in Arabidopsis

Reference	P12018
Principal Investigator / Supervisor	Professor Hugh Dickinson
Co-Investigators / Co-Supervisors	Professor Roderick Scott, Dr Melissa Spielman
Institution	University of Oxford
Department	Plant Sciences
Funding type	Research
Value (£)	168,292
Status	Completed
Type	Research Grant
Start date	07/10/1999
End date	01/03/2003
Duration	36 months

Abstract

Normal seed development in flowering plants requires a ratio of 2 maternal to 1 paternal genomes in the endosperm, reflecting the existence of parental imprinting. We have shown that in Arabidopsis, altering the parental genome balance disrupts endosperm development (Scott et al. 1998). In particular, several aspects of the cell cycle - rate of mitosis, duration of proliferation, and timing of cytokinesis - are dramatically affected in endosperm with extra maternal or paternal genomes. We propose to study the interaction between cell cycle, seed development, and imprinting. Expression of cell cycle genes in developing seeds will be investigated, and imprinted genes will be identified using allele-specific RT- PCR and in situ hybridisation. (Joint with award P12020.)

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

P12020 Relationship between cell cycle control parental imprinting and seed development in Arabidopsis

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