Award details

Examination of resistance to hyphal breakage in actinomycetes

ReferenceP07303
Principal Investigator / Supervisor Professor Colin Thomas
Co-Investigators /
Co-Supervisors
Institution University of Birmingham
DepartmentChemical Engineering
Funding typeResearch
Value (£) 143,324
StatusCompleted
TypeResearch Grant
Start date 15/05/1997
End date 15/05/2000
Duration36 months

Abstract

It has been established at Surrey that particle size distribution affects secondary metabolite production of actinomycetes; with a minimum effective size. Disposition to fragmentation, determined by peptidoglycan synthesising enzyme ability, can lead to decreased production. The research proposed will underpin a study of this phenomenon at Surrey by (a) providing morphology data using existing image analysis methods; (b) developing a new method to visualise the position of expression marked by a reporter gene; and (c) measuring mechanical properties of the hyphae. (Joint with grant P07291).

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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