Award details

Cell-cell signalling in Pseudomonas and Erwinia: novel opportunities in microbial cell technology

Reference	P06045
Principal Investigator / Supervisor	Professor Barrie Bycroft
Co-Investigators / Co-Supervisors	Dr G Stewart, Professor Paul Williams
Institution	University of Nottingham
Department	Sch of Pharmacy
Funding type	Research
Value (£)	660,336
Status	Completed
Type	Research Grant
Start date	01/03/1996
End date	31/01/2000
Duration	45 months

Abstract

In keeping with the momentum derived from the previous BBSRC-funded research programme, we propose to explore two interlinked core areas. These are (1) exploitation of the genetic characterisation of carbapenem biosynthesis and regulation through the continued biochemical characterisation of the cognate enzymatic pathway and (2) the detailed elucidation of the complex regulatory mechanisms that underly cell-cell signalling (quorum sensing) and the production of secondary metabolites. Secondary metabolite production of both Erwinia (e.g. carbapenems) and Pseudomonas (e.g. exoenzymes) are biotechnologically relevant and in both organisms quorum sensing plays a central regulatory role. Both core areas offer outstanding opportunities for underpinning the exploitation of novel microbial cell technology.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

P06049 Cell-to-cell signalling in Pseudomonas and Erwinia: novel opportunities in microbial cell technology

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search