Award details

Identification and characterisation of key genes and mutants involved in fatty acid breakdown during seed germination

ReferenceGAT09140
Principal Investigator / Supervisor Professor Alison Baker
Co-Investigators /
Co-Supervisors
Professor Ian Graham
Institution University of Leeds
DepartmentPlant Biochemistry & Biotechnology
Funding typeResearch
Value (£) 167,374
StatusCompleted
TypeResearch Grant
Start date 23/02/1998
End date 23/02/2001
Duration36 months

Abstract

Beta-oxidation of fatty acids and associated peroxisome biogenesis are central to two phases of the plant life cycle which are of agricultural importance; germination/early seedling growth, and senescence. Furthermore, futile cycling of genetically engineered fatty acids via beta-oxidation represents a generic barrier to high yields in crop plants. Manipulation of the fatty acid breakdown by under or overexpressing key genes is therefore of significant agronomic importance. This proposal will use two complementary approaches to identify and characterise key genes involved in the conversion of fatty acids to sucrose. The first will exploit Bacterial Artificial Chromosome library technology to rapidly isolate and characterise the promoter regions of a number of target genes. The second approach will use a novel, proven, screening strategy to isolate DNA tagged mutants in fatty acid breakdown. (Joint with grant GAT09139).

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Genome Analysis of Agriculturally Important Traits (GAT) [1997-1998]
Funding SchemeX – not Funded via a specific Funding Scheme
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