Award details

Identification and characterisation of key genes and mutants involved in fatty acid breakdown during seed germination

Reference	GAT09139
Principal Investigator / Supervisor	Professor Ian Graham
Co-Investigators / Co-Supervisors	Professor Alison Baker
Institution	University of York
Department	Biology
Funding type	Research
Value (£)	162,951
Status	Completed
Type	Research Grant
Start date	15/03/1998
End date	15/03/2001
Duration	36 months

Abstract

Beta-oxidation of fatty acids and associated peroxisome biogenesis are central to two phases of the plant life cycle which are of agricultural importance; germination/early seedling growth, and senescence. Furthermore, futile cycling of genetically engineered fatty acids via beta-oxidation represents a generic barrier to high yields in crop plants. Manipulation of the fatty acid breakdown by under or overexpressing key genes is therefore of significant agronomic importance. This proposal will use two complementary approaches to identify and characterise key genes involved in the conversion of fatty acids to sucrose. The first will exploit Bacterial Artificial Chromosome library technology to rapidly isolate and characterise the promoter regions of a number of target genes. The second approach will use a novel, proven, screening strategy to isolate DNA tagged mutants in fatty acid breakdown. (Joint with grant GAT09140).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Genome Analysis of Agriculturally Important Traits (GAT) [1997-1998]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

GAT09140 Identification and characterisation of key genes and mutants involved in fatty acid breakdown during seed germination

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