Award details

Dynamic growth maps of development

Reference	G20321
Principal Investigator / Supervisor	Professor JA BANGHAM
Co-Investigators / Co-Supervisors	Professor Enrico Coen
Institution	University of East Anglia
Department	Computing Sciences
Funding type	Research
Value (£)	293,436
Status	Completed
Type	Research Grant
Start date	16/02/2004
End date	15/02/2007
Duration	36 months

Abstract

The aim is to provide an experimental, computational and theoretical framework to help bridge the gap between gene function and the development of shape. A combination of approaches will be used to derive quantitative dynamic growth maps for three developmental systems ¿ the Arabidopsis leaf, Drosophila wing and mouse limb. This will involve tracking cells over time in 2D or 3D and clonal analysis to estimate regional growth parameters and organ shapes resulting from growth and/or rearrangements of cells. Dynamic maps will be developed that show the pattern of growth over space and time. These will be used together with knowledge of gene activities to derive testable predictive models for key components governing the development of shape. (Joint with grant number 20317).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

G20317 Dynamic growth maps of development

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