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Differential gene exchange across a steep selection gradient: a genomic analysis

ReferenceG18145
Principal Investigator / Supervisor Professor Jane Rogers
Co-Investigators /
Co-Supervisors
Institution Wellcome Trust Sanger Institute
DepartmentWellcome Trust Sanger Institute Department
Funding typeResearch
Value (£) 56,832
StatusCompleted
TypeResearch Grant
Start date 01/06/2004
End date 31/05/2006
Duration24 months

Abstract

Many models of speciation involve a stage in which parts of the genome are open to gene exchange while selection prevents introgression in other parts. Analyses of multi-locus sequence data have started to reveal such patterns in closely related Drosophila species. We propose to complement and extend these studies using a parapatric interaction between distinct morphs of the gastropod Littorina saxatilis occupying a steep environmental gradient. We will compare the pattern of sequence diversity and divergence in differentiated and undifferentiated parts of the genome and document the genomic extent of the differentiated regions. We will use the data to test hypotheses about the origin of the divergence using coalescent simulations. (Joint with grant 18139)

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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