Award details

Differential gene exchange across a steep selection gradient: a genomic analysis

Reference	G18139
Principal Investigator / Supervisor	Dr J Grahame
Co-Investigators / Co-Supervisors	Professor Roger Butlin
Institution	University of Leeds
Department	Inst of Integrative & Comparative Biolog
Funding type	Research
Value (£)	253,920
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	30/09/2006
Duration	42 months

Abstract

Many models of speciation involve a stage in which parts of the genome are open to gene exchange while selection prevents introgression in other parts. Analyses of multi-locus sequence data have started to reveal such patterns in closely related Drosophila species. We propose to complement and extend these studies using a parapatric interaction between distinct morphs of the gastropod Littorina saxatilis occupying a steep environmental gradient. We will compare the pattern of sequence diversity and divergence in differentiated and undifferentiated parts of the genome and document the genomic extent of the differentiated regions. We will use the data to test hypotheses about the origin of the divergence using coalescent simulations. (Joint with grant 18145).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

G18145 Differential gene exchange across a steep selection gradient: a genomic analysis

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