Award details

Exploiting Campylobacter jejuni genomics

ReferenceEGA16174
Principal Investigator / Supervisor Professor Mark Pallen
Co-Investigators /
Co-Supervisors
Institution University of Birmingham
DepartmentImmunity and Infection
Funding typeResearch
Value (£) 77,676
StatusCompleted
TypeResearch Grant
Start date 01/09/2003
End date 31/08/2007
Duration48 months

Abstract

C. jejuni is a major pathogen and acknowledged clinical and economic problem. As such a genome-wide study of gene function is justified. We propose the systematic deletion and tagging of all 1654 genes from C. jejuni and, in collaboration with the wider Campylobacter community and industrial partners, will determine their biological function using in vitro and in vivo assays. A bioinformatics and selective structural analysis will underpin these studies. Targets important in the food chain and host associated environments will be identified and exploited by end users to design complementary, practical measures to reduce the burden of Campylobacter-mediated disease. (Joint with grant numbers 16166, 16167, 16168, 16169, 16171, 16172 and 16174).

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Exploiting Genomics: Agri, Food and Environment (EGA) [2001]
Funding SchemeX – not Funded via a specific Funding Scheme
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