Award details

Exploiting Campylobacter jejuni genomics

Reference	EGA16167
Principal Investigator / Supervisor	Professor Brendan Wren
Co-Investigators / Co-Supervisors
Institution	London Sch of Hygiene and Trop Medicine
Department	Infectious and Tropical Diseases
Funding type	Research
Value (£)	380,844
Status	Completed
Type	Research Grant
Start date	04/03/2003
End date	03/06/2006
Duration	39 months

Abstract

C. jejuni is a major pathogen and acknowledged clinical and economic problem. As such a genome-wide study of gene function is justified. We propose the systematic deletion and tagging of all 1654 genes from C. jejuni and, in collaboration with the wider Campylobacter community and industrial partners, will determine their biological function using in vitro and in vivo assays. A bioinformatics and selective structural analysis will underpin these studies. Targets important in the food chain and host associated environments will be identified and exploited by end users to design complementary, practical measures to reduce the burden of Campylobacter-mediated disease. (Joint with grants 16166, 16168, 16169, 16171, 16172, 16173, 16174).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Exploiting Genomics: Agri, Food and Environment (EGA) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

EGA16166 Exploiting Campylobacter jejuni genomics

EGA16174 Exploiting Campylobacter jejuni genomics

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