Award details

The development of genetic systems to facilitate the exploitation of clostridium genome information

Reference	E13746
Principal Investigator / Supervisor	Professor Nigel Minton
Co-Investigators / Co-Supervisors
Institution	University of Nottingham
Department	Inst of Infections and Immunity
Funding type	Research
Value (£)	175,466
Status	Completed
Type	Research Grant
Start date	01/01/2001
End date	18/06/2004
Duration	42 months

Abstract

Despite their industrial and medical importance, our basic understanding of Clostridium molecular biology and physiology is limited. Genome data for C. acetobutylicum and C. difficile offers new opportunities. However, the genetic systems necessary to manipulate these species are currently inadequate. We propose to develop a Molecular Tool Box to allow the full exploitation of clostridial genome sequences. It is our intention to focus on C. difficile, as the needs are most pressing in this species. However, many of the tools will also be applicable to C. acetobutylicum. Their availability will facilitate programmes of work aimed at deriving a greater understanding of Clostridium sp. molecular biology and physiology. (Joint with grant 31/E13728.)

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

E13728 The development of genetic systems to facilitate the exploitation of clostridium genome information

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