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The effect of over-expression of delta-9-desaturase on fatty acid composition of ruminant adipocytes
Reference
D01803
Principal Investigator / Supervisor
Professor Peter Buttery
Co-Investigators /
Co-Supervisors
Professor Andrew Salter
Institution
University of Nottingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
162,078
Status
Completed
Type
Research Grant
Start date
01/10/1994
End date
01/10/1997
Duration
36 months
Abstract
The objective of the study is to assess the possibility of increasing the proportion of oleic acid (a monounsaturated fatty acid) in sheep adipose tissue by over expressing an isoform of the delta-9-desaturase gene. As more than one isoform of delta-9-desaturase appears to be present in adipose tissue, the number, role, properties and regulation of the various isoforms will be determined to assess which form(s) would be best for subsequent transfection into sheep adipose cells. Successful production of such cells should give a clear indication as to whether transgenic sheep could be produced with meat enriched in oleic acid which may have potential benefit for the health of consumers.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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