Award details

Structure/function of cold and pressure adapted enzymes isolated from deep sea fish

Reference	C13480
Principal Investigator / Supervisor	Professor Martin Warren
Co-Investigators / Co-Supervisors	Dr Sheraz Gul, Professor David Hunt, Professor Julian Partridge
Institution	Queen Mary University of London
Department	Sch of Biological and Chemical Sciences
Funding type	Research
Value (£)	180,116
Status	Completed
Type	Research Grant
Start date	01/09/2000
End date	01/09/2003
Duration	36 months

Abstract

The research programme included in this application is aimed at advancing the understanding of the molecular adaptations made to proteins that work at high pressure and low temperatures. This will be achieved by characterising a number of enzymes isolated from fish that live at depths of up to 5000 metres. The cDNA corresponding to the enzymes will be isolated and sequenced to allow observed physical changes in the enzymes properties to be correlated to differences in enzyme primary structure and ultimately tertiary structure.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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