Award details

Development and distribution of genetic circuit models for seasonal reproduction

Reference	BEP17427/2
Principal Investigator / Supervisor	Professor Andrew Millar
Co-Investigators / Co-Supervisors	Professor Isabelle Carre, Professor David Rand
Institution	University of Edinburgh
Department	Sch of Biological Sciences
Funding type	Research
Value (£)	81,864
Status	Completed
Type	Research Grant
Start date	15/02/2005
End date	14/08/2005
Duration	6 months

Abstract

Multifactorial biological control circuits are hard to study experimentally but exhibit interesting behaviour, such as oscillations and non-linearity. We will develop a highly intuitive interface, model an important control circuit for the first time and distribute the models to experimental groups. The circuit controlling seasonal flowering is a classic challenge to biology with major impacts on agriculture. It comprises a day-length timer (based on the 24-hour biological clock and rapid light responses) and a slow response to weeks of cold. Emerging data now identify the core clockwork and also proteins that integrate day-length and temperature signals. True molecular models will aid this research, ultimately as an analysis tool linked from public databases via the GRID.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme (BEP) [2000-2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BEP17427 Development and distribution of genetic circuit models for seasonal reproduction

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