Award details

Development and distribution of genetic circuit models for seasonal reproduction

ReferenceBEP17427
Principal Investigator / Supervisor Professor Andrew Millar
Co-Investigators /
Co-Supervisors
Professor Isabelle Carre, Professor David Rand
Institution University of Warwick
DepartmentBiological Sciences
Funding typeResearch
Value (£) 327,572
StatusCompleted
TypeResearch Grant
Start date 01/06/2002
End date 28/02/2005
Duration33 months

Abstract

Multifactorial biological control circuits are hard to study experimentally but exhibit interesting behaviour, such as oscillations and non-linearity. We will develop a highly intuitive interface, model an important control circuit for the first time and distribute the models to experimental groups. The circuit controlling seasonal flowering is a classic challenge to biology with major impacts on agriculture. It comprises a day-length timer (based on the 24-hour biological clock and rapid light responses) and a slow response to weeks of cold. Emerging data now identify the core clockwork and also proteins that integrate day-length and temperature signals. True molecular models will aid this research, ultimately as an analysis tool linked from public databases via the GRID.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Bioinformatics and E Science Programme (BEP) [2000-2001]
Funding SchemeX – not Funded via a specific Funding Scheme
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