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A distributed pipeline for structural-based proteome annotation using GRID technology

ReferenceBEP17014
Principal Investigator / Supervisor Professor Michael Sternberg
Co-Investigators /
Co-Supervisors
Professor John Darlington
Institution Imperial College London
DepartmentBiological Sciences
Funding typeResearch
Value (£) 386,156
StatusCompleted
TypeResearch Grant
Start date 04/07/2002
End date 03/10/2006
Duration51 months

Abstract

Imperial, UCL and EBI will use GRID technology to provide a structure-based annotation of the proteins in the major genomes (the proteomes). The annotation will primarily employ sophisticated homology and fold recognition methods to assign protein structures to the proteomes and generate 3D models. Enhanced functional annotation will exploit the structural information. The distributed annotation system (DAS) at the EBI will provide a common user interface to the annotations at the 3 sites for each community. The high performance computational needs for the regular updates will be met by sharing resources at each site using the GRID under GLOBUS. This project will develop the prototype for a national:distributed proteome annotation GRID. (Joint with grants 17048 and 17055).

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Bioinformatics and E Science Programme (BEP) [2000-2001]
Funding SchemeX – not Funded via a specific Funding Scheme
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