BBSRC Portfolio Analyser
Award details
Avian Developmental immunology and innate immunity
Reference
BBS/E/I/00001591
Principal Investigator / Supervisor
Professor Venugopal Nair
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
268,864
Status
Completed
Type
Institute Project
Start date
01/12/2010
End date
30/09/2012
Duration
22 months
Abstract
The research will focus on taking advantage of the developing avian embryo to study the development of the avian immune system, particularly in areas such as lymphocyte development and differentiation, as well as T-cell receptor repertoire dynamics during the immune responses to viral pathogens. In addition, the project will also examine the role of different components of the avian innate immune system such as the Natural Killer cells and TLR repertoire models in viral infections. Under this project, we also aim to develop tools for the analysis of the functional role of the specific components of the avian immune system through methods such as RNA interference. Research on the development of transgenic technology using avian primordial germ cells or lentivirus-mediated transgenesis with the goal of gene knock out (or knock in) chickens targeting specific genes of the avian immune system will also be one of the goals of the project.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Animal Health, Immunology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search