Award details

TSE Core programme

Reference	BBS/E/I/00001054
Principal Investigator / Supervisor	Professor Jean Manson
Co-Investigators / Co-Supervisors	Dr Moira Bruce, Dr Andrew Gill, Dr Eleanor Fiona Houston, Professor Nora Hunter, Dr Robert Somerville
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	1,654,893
Status	Completed
Type	Institute Project
Start date	01/10/2003
End date	31/03/2007
Duration	42 months

Abstract

This core project will investigate aspects of (1) the relationship between PrP and infection, (2) the molecular definition of TSE strains, (3) the Role of lymphoid tissue in peripheral pathogenesis, (4)the mechanism of infection following oral exposure, (5) the role of PrPsequence/structure in TSE transmission, (6) the basis of the species barrier, (7) the effects of age on susceptibility, (9) pathogenesis and pathology of central and peripheral nervous systems and (10) normal function of PrP.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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