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Award details
The relative transmissibility of sheep and cattle BSE to humans
Reference
BBS/E/I/00000865
Principal Investigator / Supervisor
Professor Jean Manson
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
37,807
Status
Completed
Type
Institute Project
Start date
01/10/2001
End date
30/09/2006
Duration
60 months
Abstract
If BSE has passed into sheep it is important to establish the whether sheep BSE is likely to transmit to man. In order to address this cattle BSE, sheep passaged BSE and natural scapie will be inoculated into transgenic mice in which the coding region of the endogenous PrP gene has been replaced by that of a human or bovine or sheep PrP gene. For each successful transmission a full titration will be set up in order to compare the susceptibility of each line to each agent.This will address the likelihood of sheep-passaged BSE transmitting to humans.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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