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Award details
Relationship between PrP gene dosage, scrapie agent replication and PrPSc accumulation
Reference
BBS/E/I/00000815
Principal Investigator / Supervisor
Professor Jean Manson
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
85,000
Status
Completed
Type
Institute Project
Start date
01/04/2000
End date
31/03/2003
Duration
36 months
Abstract
To examine the effect of expression level of the PrP gene on incubation time of disease, the replication of infectivity and the accumulation of PrP. To assess whether the alterations in incubation period in mice with different copy numbers of the PrP gene is due to an alteration in susceptibility of the mice to disease.We will also investigated the effect of expression of the Prnd gene on TSE disease.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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