Award details

Understanding and improving prediction of the behaviour of Clostridium botulinum

Reference	BBS/E/F/00042264
Principal Investigator / Supervisor	Professor Michael William Peck
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	1,700,469
Status	Completed
Type	Institute Project
Start date	01/04/2005
End date	31/03/2010
Duration	60 months

Abstract

The proposed work will extend understanding of the physiology and molecular biology of Clostridium botulinum. We will also contribute to UK food safety by delivering an improved capability to predict the behaviour of C. botulinum in food environments. There will be an emphasis on better understanding and improved prediction of lag time and of neurotoxin formation under food-relevant conditions. We have an excellent opportunity to advance the molecular microbiology of this species based on our generic expertise in functional and comparative genomics, our involvement in the recently completed genome sequence of C. botulinum and our building the first DNA microarray for this pathogen. This new understanding will lead to knowledge-led approaches to microbiological food safety. An important output of this project will be the transfer of information to key stakeholders (e.g. industry and regulators). We will also collaborate to develop new predictive models and carry out quantitative risk assessment for C. botulinum.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	Microbial Food Safety, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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