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FEMMES: Iron metabolism in pregnancy

Reference	BBS/E/F/00041145
Principal Investigator / Supervisor	Dr Linda Harvey
Co-Investigators / Co-Supervisors	Professor Michael William Peck
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	220,264
Status	Completed
Type	Institute Project
Start date	01/02/2000
End date	31/01/2004
Duration	48 months

Abstract

The principal objective is to investigate the effect of giving iron supplements to pregnant women (0, 20 or 100mg/day from 12 weeks gestation until delivery) on maternal and neonatal iron status, maternal zinc and copper absorption and indicators of status, placental structure and function, indices of oxidative stress, and inflammatory and immune response in the mother. Iron deficiency is common and can produce harmful effects on the mother and her developing foetus. Anaemia is always treated with iron supplements and routine supplementation during pregnancy is not uncommon. The amount of iron given varies widely and there is growing concern about the risks associated with high supplemental doses. The investigation forms part of a nine centre EU funded project coordinated by The Rowett Research Institute. Concurrently, the effects of iron supplementation on the parameters described above, will be studied directly in humans and the mechanisms involved, be investigated using cell culture and animal models at the other centres. The main application of the project will be in the field of public health providing rational guidelines for supplementation strategies.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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