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Regulation of cyclin D, expression by MAPK and SAPK pathways
Reference
BBS/E/B/0000Q033
Principal Investigator / Supervisor
Dr Simon Cook
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
38,993
Status
Completed
Type
Institute Project
Start date
01/04/2003
End date
30/09/2004
Duration
18 months
Abstract
The stress activated protein kinases (SAPKs) are a family of enzymes which are activated when cells are exposed to noxious or damaging stimuli. They serve to tell the cell to stop growing, thereby giving the cell the opportunity to fix the damage. In some cases, if the damage is too severe, these pathways can operate to kill the cell so that the damage remains localised. The ability to regulate or manipulate these enzymes may be useful in either preventing cell death or even enhancing cell death in those diseases characterised by excessve cell proliferation including cancer and autoimmunity.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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