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A role for Pin1 in MAPK-dependent stabilization of AP-1 proteins ?
Reference
BBS/E/B/0000L134
Principal Investigator / Supervisor
Dr Simon Cook
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
135,440
Status
Completed
Type
Institute Project
Start date
01/11/2004
End date
31/10/2007
Duration
36 months
Abstract
Cells must be able to respond to changes in their environment. In the case of advanced, multicellular organisms such as ourselves this may mean changes in energy (food) supply, changes due to injury or damage due to exposure to toxic chemicals. Higher organisms have evolved a complex array of `signal relay¿ systems to detect and respond to such changes and in many cases this involves changes in gene expression. In this project we will seek to understand how some of these signals are `translated¿ to influence the expression of genes. Such mechanisms are certainly important to the normal functioning of the cell but may also contribute to changes in cellular function that underpin certain forms of disease.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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