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Award details
The molecules and mechanisms that deliver polarised Ptdins(3,4,5)P3 accumulation.
Reference
BBS/E/B/0000L091
Principal Investigator / Supervisor
Professor Len Stephens
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
179,722
Status
Completed
Type
Institute Project
Start date
01/09/2003
End date
31/05/2007
Duration
45 months
Abstract
Neutrophils are a form of white blood cells involved in the process of destroying potentially infectious pathogens. A key part of the way they achieve this is to migrate towards sites of infection or injury by a process called chemotaxis. Chemotaxis is based on the ability of the neutrophils to detect chemicals and hormones produced at the site of infection or injury, to sense where they are coming from, and to use this cue to direct their movement. We are aiming to understand the molecules and mechanisms operating inside neutrophils that allows them to accomplish this critical response and contribute to recovery.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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