Award details

Developmental conservation and diversity in the Bilateria: filling the gap with a polychaete annelid

Reference	BB/X524192/1
Principal Investigator / Supervisor	Professor Peter Holland
Co-Investigators / Co-Supervisors
Institution	University of Oxford
Department	Zoology
Funding type	Research
Value (£)	192,920
Status	Completed
Type	Research Grant
Start date	01/02/2005
End date	28/02/2006
Duration	13 months

Abstract

Our current understanding of the molecular basis of development in the Bilateria derives from a few key model taxa, drawn from the Deuterostomia and Ecdysozoa. Here we propose to extend such analyses to the third great bilaterian group, the Lophotrochozoa, using a polychaete annelid. Polychaetes are a classic example of a metameric, triploblast, bilaterian, and provide an excellent model for comparison to other phyla. We will focus on two key aspects; homeobox gene cluster organisation and evolution, and nervous system development. This will establish the extent of conservation and degree of diversity of polychaetes with other phyla, facilitating reconstruction of the ancestral Bilaterian genome and bodyplan and its subsequent evolution.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Comparative Development Initiative (COD) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

COD16788 Developmetal conservation and diversity in the Bilateria: filling the gap with a polychaete annelid

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