Award details

Developmetal conservation and diversity in the Bilateria: filling the gap with a polychaete annelid

Reference	COD16788
Principal Investigator / Supervisor	Professor Peter Holland
Co-Investigators / Co-Supervisors	Dr David Ferrier, Professor Sebastian Shimeld
Institution	University of Reading
Department	Animal and Microbial Sciences
Funding type	Research
Value (£)	453,900
Status	Completed
Type	Research Grant
Start date	01/01/2002
End date	31/01/2005
Duration	37 months

Abstract

Our current understanding of the molecular basis of development in the Bilateria derives from a few key model taxa, drawn from the Deuterostomia and Ecdysozoa. Here we propose to extend such analyses to the third great bilaterian group, the Lophotrochozoa, using a polychaete annelid. Polychaetes are a classic example of a metameric, triploblast, bilaterian, and provide an excellent model for comparison to other phyla. We will focus on two key aspects; homeobox gene cluster organisation and evolution, and nervous system development. This will establish the extent of conservation and degree of diversity of polychaetes with other phyla, facilitating reconstruction of the ancestral Bilaterian genome and bodyplan and its subsequent evolution.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Comparative Development Initiative (COD) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BB/X524192/1 Developmental conservation and diversity in the Bilateria: filling the gap with a polychaete annelid

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