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Structure-function studies of a novel haemoprotein involved in bacterial oxidation of thiosulphate and sulphide

ReferenceB15211
Principal Investigator / Supervisor Professor Benjamin Berks
Co-Investigators /
Co-Supervisors
Professor Julea Butt, Dr Myles Cheesman, Professor Andrew Hemmings
Institution University of Oxford
DepartmentBiochemistry
Funding typeResearch
Value (£) 230,180
StatusCompleted
TypeResearch Grant
Start date 01/01/2002
End date 30/04/2005
Duration40 months

Abstract

The haemoprotein SoxA is a central and essential component of the sulphur oxidation pathways of a wide- range of photosynthetic and non-photosynthetic bacteria. We have determined a structure for the as prepared oxidized enzyme. We now propose an experimental programme aimed at extending our understanding of the reactivity and redox chemistry of the enzyme using a combination of crystallographic, spectroscopic, electrochemical, genetic and biochemical methodologies.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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