Award details

Parallel mode EPR studies of metalloproteins

Reference	B01727
Principal Investigator / Supervisor	Professor Andrew Thomson
Co-Investigators / Co-Supervisors	Dr Myles Cheesman
Institution	University of East Anglia
Department	Chemistry
Funding type	Research
Value (£)	147,302
Status	Completed
Type	Research Grant
Start date	01/10/1994
End date	01/05/1998
Duration	43 months

Abstract

It is proposed to undertake the little explored method of parallel mode EPR studies of several classes of metalloproteins. This method permits detection of EPR signals from metal ions with even numbers of unpaired electrons. Studies will be made of the haem-Cu pair at the active site for dioxygen reduction of terminal respiratory bacterial oxidases, including cytochrome bo; of the novel P-cluster and mutant forms of the proteins in nitrogenase; and of plant dioxygenases containing non-haem iron with the high-spin Fe(II) (S-2) state. This application seeks to underpin a LINK between research groups at the NFL (University of Sussex) and the Metallobiology Centre at UEA.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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