BBSRC Portfolio Analyser
Award details
Production and analysis of a novel recombinant molecule for selective drug therapy
Reference
WCP11634
Principal Investigator / Supervisor
Dr Peter Goodenough
Co-Investigators /
Co-Supervisors
Professor James Dunwell
,
Dr Carol Robertson
Institution
University of Reading
Department
Plant Sciences
Funding type
Research
Value (£)
152,500
Status
Completed
Type
Research Grant
Start date
01/07/1999
End date
01/07/2002
Duration
36 months
Abstract
Two cysteine proteinases have been cloned from a tropical plant in a BBSRC feasibility study. This follow on application aims to be complete the programme of the original study by comparing two methods of mutagenesis for modification of a proteinase molecule. The modifications will improve its clinical role in treating tissue damage before tissue grafting. Highly efficient heterologous transgenic plant expression systems will be developed to produce high yields of these molecules. The system that will be developed is intended to be usable as a generic method of overproducing therapeutic proteins in plants.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Wealth Creating Products of Plants Initiative (WCP) [1995-1999]
Funding Scheme
X – not Funded via a specific Funding Scheme
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