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Self-processing polyproteins - enabling technology for introducing biochemical pathways into plants

ReferenceWCP05388
Principal Investigator / Supervisor Professor Martin Ryan
Co-Investigators /
Co-Supervisors
Professor Claire Halpin
Institution University of St Andrews
DepartmentUniversity of St Andrews Department
Funding typeResearch
Value (£) 209,220
StatusCompleted
TypeResearch Grant
Start date 01/09/1996
End date 01/11/2000
Duration50 months

Abstract

Co-ordinating multiple protein expression at the transcriptional level is difficult in plants. We propose to overcome this problem with an innovative technology, expressing multiple proteins in the form of self-processing polyproteins. An application of industrial value (improvement of plant fibres) will be addressed by introducing into plants a single gene encoding a polyprotein of two lignin biosynthetic enzymes. Our aim is to co-ordinately express these enzymes to increase the syringyl content of lignin making it easier to extract in fibre processing. To exploit the polyprotein technology further we will explore compatibility with protein targeting to various organelles significantly increasing it's wealth-creating potential.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Wealth Creating Products of Plants Initiative (WCP) [1995-1999]
Funding SchemeX – not Funded via a specific Funding Scheme
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