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Self-processing polyproteins - enabling technology for introducing biochemical pathways into plants
Reference
WCP05388
Principal Investigator / Supervisor
Professor Martin Ryan
Co-Investigators /
Co-Supervisors
Professor Claire Halpin
Institution
University of St Andrews
Department
University of St Andrews Department
Funding type
Research
Value (£)
209,220
Status
Completed
Type
Research Grant
Start date
01/09/1996
End date
01/11/2000
Duration
50 months
Abstract
Co-ordinating multiple protein expression at the transcriptional level is difficult in plants. We propose to overcome this problem with an innovative technology, expressing multiple proteins in the form of self-processing polyproteins. An application of industrial value (improvement of plant fibres) will be addressed by introducing into plants a single gene encoding a polyprotein of two lignin biosynthetic enzymes. Our aim is to co-ordinately express these enzymes to increase the syringyl content of lignin making it easier to extract in fibre processing. To exploit the polyprotein technology further we will explore compatibility with protein targeting to various organelles significantly increasing it's wealth-creating potential.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Wealth Creating Products of Plants Initiative (WCP) [1995-1999]
Funding Scheme
X – not Funded via a specific Funding Scheme
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