Award details

Edinburgh centre for protein technology

Reference	TF08111
Principal Investigator / Supervisor	Professor Robert Ramage
Co-Investigators / Co-Supervisors
Institution	University of Edinburgh
Department	Sch of Chemistry
Funding type	Research
Value (£)	1,276,104
Status	Completed
Type	Research Grant
Start date	01/11/1996
End date	01/05/2000
Duration	42 months

Abstract

The aim of this proposal is to create a Centre of Excellence in Protein Technology, focusing on the following areas: (i) the design of ligands that bind tightly to a structurally defined target (such as thrombin) using a novel blend of combinatorial chemistry and database mining; (ii) synthesis of therapeutic proteins both by chemical and recombinant methods; (iii) new strategies for engineering proteins to improve their suitability in therapeutic applications; (iv) application of proteins in biocatalysis, in particular in bio-hydroxylations; (v) production of novel anti-viral carbocyclic nucleosides and analogues by pathway engineering. The framework of the Centre will be essential to the success of these interdisciplinary projects.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Technology Foresight 1 (TF1) [1995]
Funding Scheme	X – not Funded via a specific Funding Scheme

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