Award details

Automation in the discovery of drugs to treat neurodegenerative disease

Reference	TF08110
Principal Investigator / Supervisor	Professor Kenneth Powell
Co-Investigators / Co-Supervisors
Institution	University College London
Department	The Cruciform Project
Funding type	Research
Value (£)	1,554,803
Status	Completed
Type	Research Grant
Start date	01/10/1996
End date	01/12/1999
Duration	38 months

Abstract

A target will be identified through modulation of which a drug for the treatment of neurodegenerative disease can be developed. Ligands for this target will be selected through the development of novel high throughput screening technology. The screening technology itself will be a major product of the research widely applicable to the discovery of treatments for other diseases. This will consist of a high density array of compounds on suitable filters, a novel reader and data handling tools. Lead compounds identified will be tested in secondary pharmacology and tissue culture assays to confirm their suitability for further development.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Technology Foresight 1 (TF1) [1995]
Funding Scheme	X – not Funded via a specific Funding Scheme

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